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An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca^sup 2+^...

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca^sup 2+^...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1415760643

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca^sup 2+^ entry

About this item

Full title

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca^sup 2+^ entry

Publisher

London: Nature Publishing Group

Journal title

Nature (London), 2013-07, Vol.499 (7457), p.238

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group

More information

Scope and Contents

Contents

The STIM1-ORAI1 pathway of store-operated Ca^sup 2+^ entry is an essential component of cellular Ca^sup 2+^ signalling^sup 1^. STIM1 senses depletion of intracellular Ca^sup 2+^ stores in response to physiological stimuli, and relocalizes within the endoplasmic reticulum to plasma- membrane-apposed junctions, where it recruits and gates open plasma...

Alternative Titles

Full title

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca^sup 2+^ entry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1415760643

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1415760643

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

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