Structural features of Argonaute–GW182 protein interactions
Structural features of Argonaute–GW182 protein interactions
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to target mRNAs, leading to gene silencing. However, Ago proteins are not the actual mediators of gene silencing but interact with a member of the GW182 protein family (also known as GW proteins), which coordinates all downstream steps in gene silencing. GW proteins contain an N-terminal Ago-binding...
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Full title
Structural features of Argonaute–GW182 protein interactions
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TN_cdi_proquest_journals_1440459955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1440459955
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1308510110