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Structural features of Argonaute–GW182 protein interactions

Structural features of Argonaute–GW182 protein interactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1440459955

Structural features of Argonaute–GW182 protein interactions

About this item

Full title

Structural features of Argonaute–GW182 protein interactions

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.E3770-E3779

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to target mRNAs, leading to gene silencing. However, Ago proteins are not the actual mediators of gene silencing but interact with a member of the GW182 protein family (also known as GW proteins), which coordinates all downstream steps in gene silencing. GW proteins contain an N-terminal Ago-binding...

Alternative Titles

Full title

Structural features of Argonaute–GW182 protein interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1440459955

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1440459955

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1308510110

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