Early Down-Regulation of PKC[delta] as a Pro-Survival Mechanism in Huntington's Disease
Early Down-Regulation of PKC[delta] as a Pro-Survival Mechanism in Huntington's Disease
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Publisher
Totowa: Springer Nature B.V
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Language
English
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Publisher
Totowa: Springer Nature B.V
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Contents
A balance between cell survival and apoptosis is crucial to avoid neurodegeneration. Here, we analyzed whether the pro-apoptotic protein PKCδ, and the pro-survival PKC[alpha] and [beta]II, were dysregulated in the brain of R6/1 mouse model of Huntington's disease (HD). Protein levels of the three PKCs examined were reduced in all the brain regions...
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Full title
Early Down-Regulation of PKC[delta] as a Pro-Survival Mechanism in Huntington's Disease
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TN_cdi_proquest_journals_1496032842
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1496032842
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ISSN
1535-1084
E-ISSN
1559-1174
DOI
10.1007/s12017-013-8248-8
