Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic...
Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock
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Author / Creator
VANDEN BERGHE, Tom , DEMON, Dieter , SZE MEN CHOI , MEYER, Evelyn , KRAUTWALD, Stefan , DECLERCQ, Wim , TAKAHASHI, Nozomi , CAUWELS, Anje , VANDENABEELE, Peter , BOGAERT, Pieter , VANDENDRIESSCHE, Benjamin , GOETHALS, Alain , DEPUYDT, Bart , VUYLSTEKE, Marnik , ROELANDT, Ria , VAN WONTERGHEM, Elien and VANDENBROECKE, Jill
Publisher
New York, NY: American Thoracic Society
Journal title
Language
English
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Publisher
New York, NY: American Thoracic Society
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Scope and Contents
Contents
Sepsis is one of the leading causes of death around the world. The failure of clinical trials to treat sepsis demonstrates that the molecular mechanisms are multiple and are still insufficiently understood.
To clarify the long disputed hierarchical contribution of several central inflammatory mediators (IL-1β, IL-18, caspase [CASP] 7, CASP1, and...
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Full title
Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock
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Record Identifier
TN_cdi_proquest_journals_1497405621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1497405621
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201308-1535oc
