Evaluation of the in vivo ED50 for the PET Radioligand, [11C]GSK-215083, in Papio anubis
Evaluation of the in vivo ED50 for the PET Radioligand, [11C]GSK-215083, in Papio anubis
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Amsterdam: Elsevier Inc
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English
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Amsterdam: Elsevier Inc
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Conclusion: The measures of the in vivo ED50 of [11C]GSK-215083 binding in the striatal and cortical regions are consistent with the binding signal associated with this radioligand in the striatal regions to be 5-HT6 specific and that in the cortical regions to be 5-HT2A specific. Since GSK-215083 has a sub-nanomolar affinity for the 5-HT6 receptor...
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Full title
Evaluation of the in vivo ED50 for the PET Radioligand, [11C]GSK-215083, in Papio anubis
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TN_cdi_proquest_journals_1506899680
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1506899680
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ISSN
1053-8119
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2010.04.219
