Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Epigenetic deregulation can underpin the onset and progression of several human diseases.
The expression and/or function of histone deacetylases (HDACs) is often perturbed in cancer, neurological syndromes and immune disorders.
HDACs can be effectively targeted using small-molecule chemical compounds, and more selective agents a...
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Full title
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
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TN_cdi_proquest_journals_1558532904
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1558532904
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd4360
