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Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proli...

Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1618829564

Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method

About this item

Full title

Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method

Publisher

New York: Nature Publishing Group US

Journal title

Laboratory investigation, 2014-11, Vol.94 (11), p.1296-1308

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Sustained angiogenesis is essential for tumor growth as it provides the tumor with a network of blood vessels that supply both oxygen and essential nutrients. Limiting tumor-associated angiogenesis is a proven strategy for the treatment of human cancer. To date, the rapid detection and quantitation of tumor-associated endothelial cell (TAEC) prolif...

Alternative Titles

Full title

Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1618829564

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1618829564

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2014.116

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