Sequence selectivity of macrolide-induced translational attenuation
Sequence selectivity of macrolide-induced translational attenuation
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The prevailing “plug-in-the-bottle” model suggests that macrolide antibiotics inhibit translation by binding inside the ribosome tunnel and indiscriminately arresting the elongation of every nascent polypeptide after the synthesis of six to eight amino acids. To test this model, we performed a genome-wide analysis of translation in azithromycin-tre...
Alternative Titles
Full title
Sequence selectivity of macrolide-induced translational attenuation
Authors, Artists and Contributors
Author / Creator
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TN_cdi_proquest_journals_1618865598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1618865598
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1410356111
