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Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant v...

Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant v...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1625937462

Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant vaccines

About this item

Full title

Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant vaccines

Publisher

Kidlington: Elsevier Ltd

Journal title

Vaccine, 2013-06, Vol.31 (25), p.2738-2743

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights • Formaldehyde is an essential component of some infant vaccines. • Formaldehyde levels in infants after IM injection were estimated using a PBPK model. • Formaldehyde is removed from the site of injection within 30 min. • Peak body burden was <1% of endogenous formaldehyde. • Residual formaldehyde in infant vaccines continues to be safe...

Alternative Titles

Full title

Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant vaccines

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1625937462

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1625937462

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2013.03.071

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