Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
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Author / Creator
Huang, Jinghe , Kang, Byong H. , Pancera, Marie , Lee, Jeong Hyun , Tong, Tommy , Feng, Yu , Imamichi, Hiromi , Georgiev, Ivelin S. , Chuang, Gwo-Yu , Druz, Aliaksandr , Doria-Rose, Nicole A. , Laub, Leo , Sliepen, Kwinten , van Gils, Marit J. , de la Peña, Alba Torrents , Derking, Ronald , Klasse, Per-Johan , Migueles, Stephen A. , Bailer, Robert T. , Alam, Munir , Pugach, Pavel , Haynes, Barton F. , Wyatt, Richard T. , Sanders, Rogier W. , Binley, James M. , Ward, Andrew B. , Mascola, John R. , Kwong, Peter D. and Connors, Mark
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Molecular and structural characterization is reported for a new broad and potent monoclonal antibody against HIV that binds to an epitope bridging the gp41 and gp120 subunits — the antibody affects a step in virus entry after binding to CD4 and before engagement of CCR5.
Novel vaccine target on HIV-1
This paper describes a broadly neutralizin...
Alternative Titles
Full title
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
Authors, Artists and Contributors
Author / Creator
Kang, Byong H.
Pancera, Marie
Lee, Jeong Hyun
Tong, Tommy
Feng, Yu
Imamichi, Hiromi
Georgiev, Ivelin S.
Chuang, Gwo-Yu
Druz, Aliaksandr
Doria-Rose, Nicole A.
Laub, Leo
Sliepen, Kwinten
van Gils, Marit J.
de la Peña, Alba Torrents
Derking, Ronald
Klasse, Per-Johan
Migueles, Stephen A.
Bailer, Robert T.
Alam, Munir
Pugach, Pavel
Haynes, Barton F.
Wyatt, Richard T.
Sanders, Rogier W.
Binley, James M.
Ward, Andrew B.
Mascola, John R.
Kwong, Peter D.
Connors, Mark
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1627979318
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1627979318
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13601