Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
About this item
Full title
Author / Creator
Robert, Caroline , Karaszewska, Boguslawa , Schachter, Jacob , Rutkowski, Piotr , Mackiewicz, Andrzej , Stroiakovski, Daniil , Lichinitser, Michael , Dummer, Reinhard , Grange, Florent , Mortier, Laurent , Chiarion-Sileni, Vanna , Drucis, Kamil , Krajsova, Ivana , Hauschild, Axel , Lorigan, Paul , Wolter, Pascal , Long, Georgina V , Flaherty, Keith , Nathan, Paul , Ribas, Antoni , Martin, Anne-Marie , Sun, Peng , Crist, Wendy , Legos, Jeff , Rubin, Stephen D , Little, Shonda M and Schadendorf, Dirk
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In patients with melanomas containing activating
BRAF
mutations, the combination of a BRAF inhibitor and a MEK inhibitor improved overall survival, as compared with a BRAF inhibitor alone, and was associated with many fewer second skin tumors.
The treatment of metastatic melanoma is rapidly evolving. The potent and specific BRAF inhibitors...
Alternative Titles
Full title
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
Authors, Artists and Contributors
Author / Creator
Karaszewska, Boguslawa
Schachter, Jacob
Rutkowski, Piotr
Mackiewicz, Andrzej
Stroiakovski, Daniil
Lichinitser, Michael
Dummer, Reinhard
Grange, Florent
Mortier, Laurent
Chiarion-Sileni, Vanna
Drucis, Kamil
Krajsova, Ivana
Hauschild, Axel
Lorigan, Paul
Wolter, Pascal
Long, Georgina V
Flaherty, Keith
Nathan, Paul
Ribas, Antoni
Martin, Anne-Marie
Sun, Peng
Crist, Wendy
Legos, Jeff
Rubin, Stephen D
Little, Shonda M
Schadendorf, Dirk
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1641449742
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1641449742
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1412690
