TCR contact residue hydrophobicity is a hallmark of immunogenic CD8⁺ T cell epitopes
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8⁺ T cell epitopes
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Despite the availability of major histocompatibility complex (MHC)-binding peptide prediction algorithms, the development of T-cell vaccines against pathogen and tumor antigens remains challenged by inefficient identification of immunogenic epitopes. CD8⁺ T cells must distinguish immunogenic epitopes from nonimmunogenic self peptides to respond eff...
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Full title
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8⁺ T cell epitopes
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TN_cdi_proquest_journals_1673951469
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1673951469
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1500973112
