Deletion of ARNT/HIF1[beta] in pancreatic beta cells does not impair glucose homeostasis in mice, bu...
Deletion of ARNT/HIF1[beta] in pancreatic beta cells does not impair glucose homeostasis in mice, but is associated with defective glucose sensing ex vivo
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Heidelberg: Springer Nature B.V
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English
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Heidelberg: Springer Nature B.V
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Aims/hypothesis It has been suggested that the transcription factor ARNT/HIF1[beta] is critical for maintaining in vivo glucose homeostasis and pancreatic beta cell glucose-stimulated insulin secretion (GSIS). Our goal was to gain more insights into the metabolic defects seen after the loss of ARNT/HIF1[beta] in beta cells. Methods The in vivo and...
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Deletion of ARNT/HIF1[beta] in pancreatic beta cells does not impair glucose homeostasis in mice, but is associated with defective glucose sensing ex vivo
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TN_cdi_proquest_journals_1728969442
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1728969442
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ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-015-3768-4
