High Frequency and Poor Prognosis of Late Childhood BCR-ABL-Positive and MLL-AF4-Positive ALL Define...
High Frequency and Poor Prognosis of Late Childhood BCR-ABL-Positive and MLL-AF4-Positive ALL Define the Need for Advanced Molecular Diagnostics and Improved Therapeutic Strategies in Pediatric B-ALL in Pakistan
About this item
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Author / Creator
Iqbal, Zafar , Akhtar, Tanveer , Awan, Tashfin , Aleem, Aamer , Sabir, Noreen , Rasool, Mahmood , Absar, Muhammad , Akram, Afia M. , Shammas, Masood A. , Shah, Ijaz H. , Khalid, Muhammad , Taj, Abid S. , Jameel, Abid , Alanazi, Abdullah , Gill, Ammara T. , Hashmi, Jamil Amjad , Hussain, Akhtar , Sabar, Muhammad Farooq , Khalid, Ahmad M. , Qazi, Mehmood Hussain , Karim, Sajjad , Siddiqi, Muhammad Hassan , Mahmood, Aamir , Iqbal, Mudassar , Saeed, Anjum and Irfan, Muhammad Imran
Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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More information
Scope and Contents
Contents
Background
Fusion oncogenes (FOs) resulting from chromosomal abnormalities have an important role in leukemogenesis in pediatric B cell acute lymphoblastic leukemia (ALL). The most common FOs are BCR-ABL, MLL-AF4, ETV6-RUNX1, and TCF3-PBX1, all of which have important prognostic and drug selection implications. Moreover, frequencies of FOs have...
Alternative Titles
Full title
High Frequency and Poor Prognosis of Late Childhood BCR-ABL-Positive and MLL-AF4-Positive ALL Define the Need for Advanced Molecular Diagnostics and Improved Therapeutic Strategies in Pediatric B-ALL in Pakistan
Authors, Artists and Contributors
Author / Creator
Akhtar, Tanveer
Awan, Tashfin
Aleem, Aamer
Sabir, Noreen
Rasool, Mahmood
Absar, Muhammad
Akram, Afia M.
Shammas, Masood A.
Shah, Ijaz H.
Khalid, Muhammad
Taj, Abid S.
Jameel, Abid
Alanazi, Abdullah
Gill, Ammara T.
Hashmi, Jamil Amjad
Hussain, Akhtar
Sabar, Muhammad Farooq
Khalid, Ahmad M.
Qazi, Mehmood Hussain
Karim, Sajjad
Siddiqi, Muhammad Hassan
Mahmood, Aamir
Iqbal, Mudassar
Saeed, Anjum
Irfan, Muhammad Imran
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1746922496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1746922496
Other Identifiers
ISSN
1177-1062
E-ISSN
1179-2000
DOI
10.1007/s40291-015-0149-0
