Genomic analyses identify molecular subtypes of pancreatic cancer
Genomic analyses identify molecular subtypes of pancreatic cancer
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Author / Creator
Bailey, Peter , Chang, David K. , Nones, Katia , Johns, Amber L. , Patch, Ann-Marie , Gingras, Marie-Claude , Miller, David K. , Christ, Angelika N. , Bruxner, Tim J. C. , Quinn, Michael C. , Nourse, Craig , Murtaugh, L. Charles , Harliwong, Ivon , Idrisoglu, Senel , Manning, Suzanne , Nourbakhsh, Ehsan , Wani, Shivangi , Fink, Lynn , Holmes, Oliver , Chin, Venessa , Anderson, Matthew J. , Kazakoff, Stephen , Leonard, Conrad , Newell, Felicity , Waddell, Nick , Wood, Scott , Xu, Qinying , Wilson, Peter J. , Cloonan, Nicole , Kassahn, Karin S. , Taylor, Darrin , Quek, Kelly , Robertson, Alan , Pantano, Lorena , Mincarelli, Laura , Sanchez, Luis N. , Evers, Lisa , Wu, Jianmin , Pinese, Mark , Cowley, Mark J. , Jones, Marc D. , Colvin, Emily K. , Nagrial, Adnan M. , Humphrey, Emily S. , Chantrill, Lorraine A. , Mawson, Amanda , Humphris, Jeremy , Chou, Angela , Pajic, Marina , Scarlett, Christopher J. , Pinho, Andreia V. , Giry-Laterriere, Marc , Rooman, Ilse , Samra, Jaswinder S. , Kench, James G. , Lovell, Jessica A. , Merrett, Neil D. , Toon, Christopher W. , Epari, Krishna , Nguyen, Nam Q. , Barbour, Andrew , Zeps, Nikolajs , Moran-Jones, Kim , Jamieson, Nigel B. , Graham, Janet S. , Duthie, Fraser , Oien, Karin , Hair, Jane , Grützmann, Robert , Maitra, Anirban , Iacobuzio-Donahue, Christine A. , Wolfgang, Christopher L. , Morgan, Richard A. , Lawlor, Rita T. , Corbo, Vincenzo , Bassi, Claudio , Rusev, Borislav , Capelli, Paola , Salvia, Roberto , Tortora, Giampaolo , Mukhopadhyay, Debabrata , Petersen, Gloria M. , Munzy, Donna M. , Fisher, William E. , Karim, Saadia A. , Eshleman, James R. , Hruban, Ralph H. , Pilarsky, Christian , Sansom, Owen J. , Scarpa, Aldo , Bailey, Ulla-Maja Hagbo , Hofmann, Oliver , Sutherland, Robert L. , Wheeler, David A. , Gill, Anthony J. , Gibbs, Richard A. , Pearson, John V. , Waddell, Nicola , Biankin, Andrew V. , Grimmond, Sean M. and Australian Pancreatic Cancer Genome Initiative
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways:
KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT
signalling,
G1/S
transition,
SWI-SNF
, chromatin modification, DNA repair and RNA processing. Expression analysis defined 4 subtypes: (1) squamous; (2) pan...
Alternative Titles
Full title
Genomic analyses identify molecular subtypes of pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Chang, David K.
Nones, Katia
Johns, Amber L.
Patch, Ann-Marie
Gingras, Marie-Claude
Miller, David K.
Christ, Angelika N.
Bruxner, Tim J. C.
Quinn, Michael C.
Nourse, Craig
Murtaugh, L. Charles
Harliwong, Ivon
Idrisoglu, Senel
Manning, Suzanne
Nourbakhsh, Ehsan
Wani, Shivangi
Fink, Lynn
Holmes, Oliver
Chin, Venessa
Anderson, Matthew J.
Kazakoff, Stephen
Leonard, Conrad
Newell, Felicity
Waddell, Nick
Wood, Scott
Xu, Qinying
Wilson, Peter J.
Cloonan, Nicole
Kassahn, Karin S.
Taylor, Darrin
Quek, Kelly
Robertson, Alan
Pantano, Lorena
Mincarelli, Laura
Sanchez, Luis N.
Evers, Lisa
Wu, Jianmin
Pinese, Mark
Cowley, Mark J.
Jones, Marc D.
Colvin, Emily K.
Nagrial, Adnan M.
Humphrey, Emily S.
Chantrill, Lorraine A.
Mawson, Amanda
Humphris, Jeremy
Chou, Angela
Pajic, Marina
Scarlett, Christopher J.
Pinho, Andreia V.
Giry-Laterriere, Marc
Rooman, Ilse
Samra, Jaswinder S.
Kench, James G.
Lovell, Jessica A.
Merrett, Neil D.
Toon, Christopher W.
Epari, Krishna
Nguyen, Nam Q.
Barbour, Andrew
Zeps, Nikolajs
Moran-Jones, Kim
Jamieson, Nigel B.
Graham, Janet S.
Duthie, Fraser
Oien, Karin
Hair, Jane
Grützmann, Robert
Maitra, Anirban
Iacobuzio-Donahue, Christine A.
Wolfgang, Christopher L.
Morgan, Richard A.
Lawlor, Rita T.
Corbo, Vincenzo
Bassi, Claudio
Rusev, Borislav
Capelli, Paola
Salvia, Roberto
Tortora, Giampaolo
Mukhopadhyay, Debabrata
Petersen, Gloria M.
Munzy, Donna M.
Fisher, William E.
Karim, Saadia A.
Eshleman, James R.
Hruban, Ralph H.
Pilarsky, Christian
Sansom, Owen J.
Scarpa, Aldo
Bailey, Ulla-Maja Hagbo
Hofmann, Oliver
Sutherland, Robert L.
Wheeler, David A.
Gill, Anthony J.
Gibbs, Richard A.
Pearson, John V.
Waddell, Nicola
Biankin, Andrew V.
Grimmond, Sean M.
Australian Pancreatic Cancer Genome Initiative
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1772142522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772142522
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature16965
