Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons af...
Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
A significant unmet need in treating neurodegenerative disease is effective methods for delivery of biologic drugs, such as peptides, proteins, or nucleic acids into the central nervous system (CNS). To date, there are no operative technologies for the delivery of macromolecular drugs to the CNS via peripheral administration routes. Using an in viv...
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Full title
Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration
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TN_cdi_proquest_journals_1772860208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772860208
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1515526113
