Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom pept...
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Formation of correct disulfide bonds in the endoplasmic reticulum is a crucial step for folding proteins destined for secretion. Protein disulfide isomerases (PDIs) play a central role in this process. We report a previously unidentified, hypervariable family of PDIs that represents the most diverse gene family of oxidoreductases described in a sin...
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Full title
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
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TN_cdi_proquest_journals_1780547684
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1780547684
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1525790113
