88. Synthetic siRNAs for Huntington’s Disease Therapy
88. Synthetic siRNAs for Huntington’s Disease Therapy
About this item
Full title
Author / Creator
Publisher
Milwaukee: Elsevier Limited
Journal title
Language
English
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Publication information
Publisher
Milwaukee: Elsevier Limited
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Scope and Contents
Contents
Huntington's disease (HD) is a dominant neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) tract of the huntingtin (htt) protein. PolyQ expansion in htt induces cortical and striatal neuron cell loss, and the formation of httcontaining aggregates within brain cells. HD patients have progressive psychiatric, cognitive and...
Alternative Titles
Full title
88. Synthetic siRNAs for Huntington’s Disease Therapy
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_1792801902
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792801902
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2006.08.106
