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Canonical NF-[kappa]B signaling is uniquely required for the long-term persistence of functional mat...

Canonical NF-[kappa]B signaling is uniquely required for the long-term persistence of functional mat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1801623973

Canonical NF-[kappa]B signaling is uniquely required for the long-term persistence of functional mature B cells

About this item

Full title

Canonical NF-[kappa]B signaling is uniquely required for the long-term persistence of functional mature B cells

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.5065

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Although canonical NF-...B signaling is crucial to generate a normal mature B-cell compartment, its role in the persistence of resting mature B cells is controversial. To resolve this conflict, we ablated NF-...B essential modulator (NEMO) and I...B kinase 2 (IKK2), two essential mediators of the canonical pathway, either early on in B-cell develop...

Alternative Titles

Full title

Canonical NF-[kappa]B signaling is uniquely required for the long-term persistence of functional mature B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1801623973

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1801623973

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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