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Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to...

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1802783675

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting [beta]2agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

About this item

Full title

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting [beta]2agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

Publisher

London: Elsevier Limited

Journal title

The Lancet (British edition), 2016-07, Vol.388 (10039), p.31

Language

English

Formats

Publication information

Publisher

London: Elsevier Limited

More information

Scope and Contents

Contents

Dupilumab, a fully human anti-interleukin-4 receptor α monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation. Adults with uncontrolled persistent asthma who are receiving medium-to-high-dose inhaled corticosteroids plus a long-acting β2agonist require additional treatment options as a...

Alternative Titles

Full title

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting [beta]2agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1802783675

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1802783675

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(16)30307-5

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