Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
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United States: Massachusetts Medical Society
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Language
English
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Publisher
United States: Massachusetts Medical Society
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Contents
Absence of proopiomelanocortin results in early-onset obesity, hyperphagia, hypopigmentation, and hypocortisolism. Two affected patients received setmelanotide, a new melanocortin-4 receptor agonist, which led to sustainable reduction of hunger and substantial weight loss.
Melanocyte-stimulating hormone, which is produced from proopiomelanocorti...
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Full title
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
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TN_cdi_proquest_journals_1809588316
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1809588316
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1512693