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Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1809588316

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

About this item

Full title

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2016-07, Vol.375 (3), p.240-246

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

Absence of proopiomelanocortin results in early-onset obesity, hyperphagia, hypopigmentation, and hypocortisolism. Two affected patients received setmelanotide, a new melanocortin-4 receptor agonist, which led to sustainable reduction of hunger and substantial weight loss.
Melanocyte-stimulating hormone, which is produced from proopiomelanocorti...

Alternative Titles

Full title

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1809588316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1809588316

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1512693

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