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A conserved [alpha][Beta] transmembrane interface forms the core of a compact T-cell receptor-CD3 st...

A conserved [alpha][Beta] transmembrane interface forms the core of a compact T-cell receptor-CD3 st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1844061960

A conserved [alpha][Beta] transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane

About this item

Full title

A conserved [alpha][Beta] transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (43), p.E6649

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

The T-cell antigen receptor (TCR) is an assembly of eight type I single-pass membrane proteins that occupies a central position in adaptive immunity. Many TCR-triggering models invoke an alteration in receptor complex structure as the initiating event, but both the precise subunit organization and the pathway by which ligand-induced alterations are...

Alternative Titles

Full title

A conserved [alpha][Beta] transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1844061960

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1844061960

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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