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Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein–Ba...

Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein–Ba...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1873391082

Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein–Barr virus-associated gastric cancer: the prognostic implications

About this item

Full title

Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein–Barr virus-associated gastric cancer: the prognostic implications

Publisher

New York: Nature Publishing Group US

Journal title

Modern pathology, 2017-03, Vol.30 (3), p.427-439

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cancer cells use PD-L1 to evade antitumor immunity through interaction with programmed cell death protein 1 (PD-1) on T cells. Recent whole-genome sequence studies revealed frequent gene amplification of
PD-L1
in Epstein–Barr virus-associated gastric cancer (EBVaGC). To investigate the significance of PD-L1 in cancer cells and their microenvi...

Alternative Titles

Full title

Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein–Barr virus-associated gastric cancer: the prognostic implications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1873391082

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1873391082

Other Identifiers

ISSN

0893-3952

E-ISSN

1530-0285

DOI

10.1038/modpathol.2016.202

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