Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186
Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186
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Author / Creator
Fujimoto, Kosuke , Kinoshita, Makoto , Tanaka, Hiroo , Okuzaki, Daisuke , Shimada, Yosuke , Kayama, Hisako , Okumura, Ryu , Furuta, Yoki , Narazaki, Masashi , Tamura, Atsushi , Hatakeyama, Shigetsugu , Ikawa, Masahito , Tsuchiya, Kiichiro , Watanabe, Mamoru , Kumanogoh, Atsushi , Tsukita, Sachiko and Takeda, Kiyoshi
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Genome-wide association studies and subsequent deep sequencing analysis have identified susceptible loci for inflammatory bowel diseases (IBDs) including ulcerative colitis (UC). A gene encoding RING finger protein 186 (RNF186) is located within UC-susceptible loci. However, it is unclear whether RNF186 is involved in IBD pathogenesis. Here, we sho...
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Full title
Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186
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TN_cdi_proquest_journals_1873678813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1873678813
Other Identifiers
ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2016.58
