TMEM175 deficiency impairs lysosomal and mitochondrial function and increases [alpha]-synuclein aggr...
TMEM175 deficiency impairs lysosomal and mitochondrial function and increases [alpha]-synuclein aggregation
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Publisher
Washington: National Academy of Sciences
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Language
English
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Washington: National Academy of Sciences
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Contents
Parkinson disease (PD) is a neurodegenerative disorder pathologically characterized by nigrostriatal dopamine neuron loss and the postmortem presence of Lewy bodies, depositions of insoluble a-synuclein, and other proteins that likely contribute to cellular toxicity and death during the disease. Genetic and biochemical studies have implicated impai...
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Full title
TMEM175 deficiency impairs lysosomal and mitochondrial function and increases [alpha]-synuclein aggregation
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TN_cdi_proquest_journals_1881309820
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1881309820
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ISSN
0027-8424
E-ISSN
1091-6490
