DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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In the absence of DHX9, circular RNAs accumulate and transcription and translation are dysregulated—effects that are exacerbated by concomitant depletion of the RNA-editing enzyme ADAR.
DHX9 suppresses Alu-derived defects
In the human genome, there are more than a million copies of the
Alu
transposable element. Movement of
Alu
ele...
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Full title
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome
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TN_cdi_proquest_journals_1885669410
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1885669410
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature21715
