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NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protec...

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1892699786

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

About this item

Full title

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2017-05, Vol.18 (5), p.541-551

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The intracellular sensor NLRP12 can negatively regulate inflammation. Ting and colleagues demonstrate that an absence of NLRP12 triggers a dysbiosis that feeds forward into a process of inflammation and colitis.
Inflammatory bowel diseases involve the dynamic interaction of host genetics, the microbiome and inflammatory responses. Here we found...

Alternative Titles

Full title

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1892699786

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1892699786

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3690

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