NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protec...
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The intracellular sensor NLRP12 can negatively regulate inflammation. Ting and colleagues demonstrate that an absence of NLRP12 triggers a dysbiosis that feeds forward into a process of inflammation and colitis.
Inflammatory bowel diseases involve the dynamic interaction of host genetics, the microbiome and inflammatory responses. Here we found...
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NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth
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TN_cdi_proquest_journals_1892699786
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1892699786
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ISSN
1529-2908
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1529-2916
DOI
10.1038/ni.3690