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Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-[bet...

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-[bet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899786793

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-[beta]

About this item

Full title

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-[beta]

Publisher

London: Nature Publishing Group

Journal title

Scientific reports, 2015-11, Vol.5, p.16941

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group

More information

Scope and Contents

Contents

Mesenchymal stem cells (MSCs) are recruited to the tumor microenvironment and influence tumor progression; however, how MSCs induce the invasion of cancer cells is not completely understood. Here, we used a 3D coculture model to determine how MSCs affect the migration of invasive breast cancer cells. Coculture with MSCs increases the elongation, di...

Alternative Titles

Full title

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-[beta]

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1899786793

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899786793

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/srep16941

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