Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX...
Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial
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Author / Creator
Alistar, Angela, Dr , Morris, Bonny B, MSPH , Desnoyer, Rodwige, MD , Klepin, Heidi D, MD , Hosseinzadeh, Keyanoosh, MD , Clark, Clancy, MD , Cameron, Amy, PA , Leyendecker, John, Prof , D'Agostino, Ralph, Prof , Topaloglu, Umit, PhD , Boteju, Lakmal W, PhD , Boteju, Asela R, ASc , Shorr, Rob, PhD , Zachar, Zuzana, PhD , Bingham, Paul M, PhD , Ahmed, Tamjeed, MD , Crane, Sandrine, MD , Shah, Riddhishkumar, MD , Migliano, John J, MD , Pardee, Timothy S, MD , Miller, Lance, PhD , Hawkins, Gregory, PhD , Jin, Guangxu, PhD , Zhang, Wei, Prof and Pasche, Boris, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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More information
Scope and Contents
Contents
Summary Background Pancreatic cancer statistics are dismal, with a 5-year survival of less than 10%, and more than 50% of patients presenting with metastatic disease. Metabolic reprogramming is an emerging hallmark of pancreatic adenocarcinoma. CPI-613 is a novel anticancer agent that selectively targets the altered form of mitochondrial energy met...
Alternative Titles
Full title
Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial
Authors, Artists and Contributors
Author / Creator
Morris, Bonny B, MSPH
Desnoyer, Rodwige, MD
Klepin, Heidi D, MD
Hosseinzadeh, Keyanoosh, MD
Clark, Clancy, MD
Cameron, Amy, PA
Leyendecker, John, Prof
D'Agostino, Ralph, Prof
Topaloglu, Umit, PhD
Boteju, Lakmal W, PhD
Boteju, Asela R, ASc
Shorr, Rob, PhD
Zachar, Zuzana, PhD
Bingham, Paul M, PhD
Ahmed, Tamjeed, MD
Crane, Sandrine, MD
Shah, Riddhishkumar, MD
Migliano, John J, MD
Pardee, Timothy S, MD
Miller, Lance, PhD
Hawkins, Gregory, PhD
Jin, Guangxu, PhD
Zhang, Wei, Prof
Pasche, Boris, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1907317281
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1907317281
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(17)30314-5
