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Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1909733952

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

About this item

Full title

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-06, Vol.546 (7657), p.312-315

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Crystal structures of the human GLP-1 receptor in complex with two negative allosteric modulators reveal a common binding pocket, and, together with mutagenesis and modelling studies, further our understanding of the receptor activation mechanism.Author: Please check the wording of the following statement, which will appear online only.
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Alternative Titles

Full title

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1909733952

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1909733952

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature22378

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