Periostin activates integrin α5β1 through a PI3K/AKT-dependent pathway in invasion of cholangiocarci...
Periostin activates integrin α5β1 through a PI3K/AKT-dependent pathway in invasion of cholangiocarcinoma
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Publisher
Athens: D.A. Spandidos
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Language
English
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Publisher
Athens: D.A. Spandidos
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Scope and Contents
Contents
Periostin (PN) is mainly produced from stromal fibroblasts in cholangiocarcinoma (CCA) and shows strong impact in cancer promotion. This work aimed to investigate the mechanism that PN uses to drive CCA invasion. It was found that ITGα5β1 and α6β4 showed high expression in non-tumorigenic biliary epithelial cells and in almost all CCA cell lines. P...
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Full title
Periostin activates integrin α5β1 through a PI3K/AKT-dependent pathway in invasion of cholangiocarcinoma
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TN_cdi_proquest_journals_1932324185
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932324185
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2012.1530
