Methylated +58CpG site decreases DCN mRNA expression and enhances TGF-β/Smad signaling in NSCLC cell...
Methylated +58CpG site decreases DCN mRNA expression and enhances TGF-β/Smad signaling in NSCLC cells with high metastatic potential
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Author / Creator
QIAN, QIAN , SHI, XIANGGUANG , LEI, ZHE , ZHAN, LEI , LIU, RENG-YUN , ZHAO, JUN , YANG, BINGHUA , LIU, ZEYI and ZHANG, HONG-TAO
Publisher
Athens: D.A. Spandidos
Journal title
Language
English
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Publisher
Athens: D.A. Spandidos
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Scope and Contents
Contents
Decorin (DCN) has been suggested to display an anti-metastatic role by antagonizing bioactive TGF-β in advanced human cancers. However, the epigenetic mechanisms by which defective expression of DCN causes cancer metastasis remain unclear. We focused on non-small cell lung cancer (NSCLC) cell lines with low metastatic potential (95C) and high metas...
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Full title
Methylated +58CpG site decreases DCN mRNA expression and enhances TGF-β/Smad signaling in NSCLC cells with high metastatic potential
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Record Identifier
TN_cdi_proquest_journals_1932871301
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932871301
Other Identifiers
ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2014.2255