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Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1934032205

Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

About this item

Full title

Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2017-08, Vol.377 (9), p.829-838

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

Alectinib, a potent ALK tyrosine kinase inhibitor, was more effective and somewhat less toxic than crizotinib when used as primary therapy in patients with
ALK
-positive non–small-cell lung cancer. Importantly, it reduced the risk of CNS relapse.

Alternative Titles

Full title

Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1934032205

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1934032205

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1704795

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