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Pannexin-1 mediates large pore formation and interleukin-1[beta] release by the ATP-gated P2X7 recep...

Pannexin-1 mediates large pore formation and interleukin-1[beta] release by the ATP-gated P2X7 recep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_195264989

Pannexin-1 mediates large pore formation and interleukin-1[beta] release by the ATP-gated P2X7 receptor

About this item

Full title

Pannexin-1 mediates large pore formation and interleukin-1[beta] release by the ATP-gated P2X7 receptor

Publisher

New York: Springer Nature B.V

Journal title

The EMBO journal, 2006-11, Vol.25 (21), p.5071

Language

English

Formats

Publication information

Publisher

New York: Springer Nature B.V

More information

Scope and Contents

Contents

P2X(7) receptors are ATP-gated cation channels; their activation in macrophage also leads to rapid opening of a membrane pore permeable to dyes such as ethidium, and to release of the pro-inflammatory cytokine, interleukin-1beta (IL-1beta). It has not been known what this dye-uptake path is, or whether it is involved in downstream signalling to IL-...

Alternative Titles

Full title

Pannexin-1 mediates large pore formation and interleukin-1[beta] release by the ATP-gated P2X7 receptor

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_195264989

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_195264989

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/sj.emboj.7601378

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