Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
About this item
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Author / Creator
He, Xingyue , Riceberg, Jessica , Soucy, Teresa , Koenig, Erik , Minissale, James , Gallery, Melissa , Bernard, Hugues , Yang, Xiaofeng , Liao, Hua , Rabino, Claudia , Shah, Pooja , Xega, Kristina , Yan, Zhong-hua , Sintchak, Mike , Bradley, John , Xu, He , Duffey, Matt , England, Dylan , Mizutani, Hirotake , Hu, Zhigen , Guo, Jianping , Chau, Ryan , Dick, Lawrence R , Brownell, James E , Newcomb, John , Langston, Steve , Lightcap, Eric S , Bence, Neil and Pulukuri, Sai M
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
An inhibitor of the SUMO-activating (E1) enzyme SAE blocks enzyme activity and total SUMOylation in cells—thereby defining roles for SAE in mitotic progression and chromosome segregation—and also decreases cancer cell proliferation.
Small ubiquitin-like modifier (SUMO) family proteins regulate target-protein functions by post-translational modif...
Alternative Titles
Full title
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
Authors, Artists and Contributors
Author / Creator
Riceberg, Jessica
Soucy, Teresa
Koenig, Erik
Minissale, James
Gallery, Melissa
Bernard, Hugues
Yang, Xiaofeng
Liao, Hua
Rabino, Claudia
Shah, Pooja
Xega, Kristina
Yan, Zhong-hua
Sintchak, Mike
Bradley, John
Xu, He
Duffey, Matt
England, Dylan
Mizutani, Hirotake
Hu, Zhigen
Guo, Jianping
Chau, Ryan
Dick, Lawrence R
Brownell, James E
Newcomb, John
Langston, Steve
Lightcap, Eric S
Bence, Neil
Pulukuri, Sai M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1954383719
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1954383719
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2463
