Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
About this item
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Mutations in
TP53
(encoding the tumour-suppressor protein p53) are the most common genetic lesions found in cancers, and contribute to cancer development, progression, metastasis, and resistance to therapy.
The results of decades of research provide detailed insights into the functional consequences of
TP53
mutations; h...
Alternative Titles
Full title
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
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Author / Creator
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TN_cdi_proquest_journals_1978779184
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1978779184
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2017.151
