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Superinfection as a driver of genomic diversification in antigenically variant pathogens

Superinfection as a driver of genomic diversification in antigenically variant pathogens

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201279767

Superinfection as a driver of genomic diversification in antigenically variant pathogens

About this item

Full title

Superinfection as a driver of genomic diversification in antigenically variant pathogens

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (6), p.2123-2127

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A new pathogen strain can penetrate an immune host population only if it can escape immunity generated against the original strain. This model is best understood with influenza viruses, in which genetic drift creates antigenically distinct strains that can spread through host populations despite the presence of immunity against previous strains. Wh...

Alternative Titles

Full title

Superinfection as a driver of genomic diversification in antigenically variant pathogens

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201279767

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201279767

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0710333105

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