Reversing Established Sepsis with Antagonists of Endogenous High-Mobility Group Box 1
Reversing Established Sepsis with Antagonists of Endogenous High-Mobility Group Box 1
About this item
Full title
Author / Creator
Yang, Huan , Ochani, Mahendar , Li, Jianhua , Qiang, Xiaoling , Tanovic, Mahira , Harris, Helena E. , Susarla, Srinivas M. , Ulloa, Luis , Wang, Hong , DiRaimo, Robert , Czura, Christopher J. , Wang, Haichao , Roth, Jesse , Warren, H. Shaw , Fink, Mitchell P. , Fenton, Matthew J. , Andersson, Ulf and Tracey, Kevin J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United States annually. The pathological sequelae of sepsis are characterized by a systemic inflammatory response, but experimental therapeutics that target specific early inflammatory mediators [tumor necrosis factor (TNF) and...
Alternative Titles
Full title
Reversing Established Sepsis with Antagonists of Endogenous High-Mobility Group Box 1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_201282924
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201282924
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2434651100
