Protein Kinase Involved in Lung Injury Susceptibility: Evidence from Enzyme Isoform Genetic Knockout...
Protein Kinase Involved in Lung Injury Susceptibility: Evidence from Enzyme Isoform Genetic Knockout and in vivo Inhibitor Treatment
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Acute lung injury (ALI) associated with sepsis and iatrogenic ventilator-induced lung injury resulting from mechanical ventilation are major medical problems with an unmet need for small molecule therapeutics. Prevailing hypotheses identify endothelial cell (EC) layer dysfunction as a cardinal event in the pathophysiology, with intracellular protei...
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Full title
Protein Kinase Involved in Lung Injury Susceptibility: Evidence from Enzyme Isoform Genetic Knockout and in vivo Inhibitor Treatment
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TN_cdi_proquest_journals_201320420
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201320420
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1031595100
