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Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by...

Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201329571

Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC

About this item

Full title

Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.4919-4924

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Gap-junctional channels, permeable to large hydrophilic solutes of up to Mr [almost equal to] 1,000, are responsible for cell-to-cell communication. Phosphorylation of connexin 43 (Cx43) by PKC abolishes the permeability of gap-junctional channels and hemichannels to large hydrophilic solutes, but not to small inorganic ions. Here, we report on a m...

Alternative Titles

Full title

Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201329571

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201329571

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0603154104

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