MYC Regulation of a "Poor-Prognosis" Metastatic Cancer Cell State
MYC Regulation of a "Poor-Prognosis" Metastatic Cancer Cell State
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Author / Creator
Wolfer, Anita , Wittner, Ben S. , Irimia, Daniel , Flavin, Richard J. , Lupien, Mathieu , Gunawardane, Ruwanthi N. , Meyer, Clifford A. , Lightcap, Eric S. , Tamayo, Pablo , Mesirov, Jill P. , Liu, X. Shirley , Shioda, Toshi , Toner, Mehmet , Loda, Massimo , Brown, Myles , Brugge, Joan S. and Ramaswamy, Sridhar
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Gene expression signatures are used in the clinic as prognostic tools to determine the risk of individual patients with localized breast tumors developing distant metastasis. We lack a clear understanding, however, of whether these correlative biomarkers link to a common biological network that regulates metastasis. We find that the c-MYC oncoprote...
Alternative Titles
Full title
MYC Regulation of a "Poor-Prognosis" Metastatic Cancer Cell State
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Record Identifier
TN_cdi_proquest_journals_201336368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201336368
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0914203107
