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The human Dcn 1-like protein DCNL3 promotes Cul3 neddylation at membranes

The human Dcn 1-like protein DCNL3 promotes Cul3 neddylation at membranes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201340688

The human Dcn 1-like protein DCNL3 promotes Cul3 neddylation at membranes

About this item

Full title

The human Dcn 1-like protein DCNL3 promotes Cul3 neddylation at membranes

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (30), p.12365

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Cullin (Cul)-based E3 ubiquitin ligases are activated through the attachment of Nedd8 to the Cul protein. In yeast, Dcn1 (defective in Cul neddylation 1 protein) functions as a scaffold-like Nedd8 E3-ligase by interacting with its Cul substrates and the Nedd8 E2 Ubc12. Human cells express 5 Dcn1-like (DCNL) proteins each containing a C-terminal pot...

Alternative Titles

Full title

The human Dcn 1-like protein DCNL3 promotes Cul3 neddylation at membranes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201340688

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201340688

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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