Structural Basis for the Activation of Human Procaspase-7
Structural Basis for the Activation of Human Procaspase-7
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Caspases form a family of proteinases required for the initiation and execution phases of apoptosis. Distinct proapoptotic stimuli lead to activation of the initiator caspases-8 and -9, which in turn activate the common executioner caspases-3 and -7 by proteolytic cleavage. Whereas crystal structures of several active caspases have been reported, n...
Alternative Titles
Full title
Structural Basis for the Activation of Human Procaspase-7
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Record Identifier
TN_cdi_proquest_journals_201357541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201357541
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.221580098
