Membrane Channel Structure of Helicobacter pylori Vacuolating Toxin: Role of Multiple GXXXG Motifs i...
Membrane Channel Structure of Helicobacter pylori Vacuolating Toxin: Role of Multiple GXXXG Motifs in Cylindrical Channels
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Helicobacter pylori is a human pathogen responsible for severe gastric diseases such as peptic ulcers, gastric adenocarcinoma, and gastric lymphoma. Vacuolating toxin (VacA) is crucial in facilitating the colonization of the gastric lining by inducing cell apoptosis and immune suppression. VacA inserts into membranes and forms a hexameric, anion-se...
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Full title
Membrane Channel Structure of Helicobacter pylori Vacuolating Toxin: Role of Multiple GXXXG Motifs in Cylindrical Channels
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TN_cdi_proquest_journals_201375118
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201375118
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0308694101
