Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protei...
Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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beta-Amyloid (Abeta) acquires toxicity by self-aggregation. To identify and characterize the toxic form(s) of Abeta aggregates, we examined in vitro aggregation conditions by using large quantities of homogenous, chemically synthesized Abeta1-40 peptide. We found that slow rotation of Abeta1-40 solution reproducibly gave self-aggregated Abeta1-40 c...
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Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta
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TN_cdi_proquest_journals_201398015
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201398015
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ISSN
0027-8424
E-ISSN
1091-6490
