Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azaci...
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Lipid signaling pathways are involved in cell growth, differentiation, and apoptosis, and could have a role in the progression of myelodysplastic syndromes (MDS) into acute myeloid leukemia (AML). Indeed, recent studies showed that phosphoinositide-phospholipase (PI-PL)Cbeta1 mono-allelic deletion correlates with a higher risk of AML evolution. Als...
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Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS
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TN_cdi_proquest_journals_201412193
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201412193
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0907109106
