Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
CD22 is an inhibitory coreceptor on the surface of B cells that attenuates B cell antigen receptor (BCR) signaling and, therefore, B cell activation. Elucidating the molecular mechanisms underlying the inhibitory activity of CD22 is complicated by the ubiquity of CD22 ligands. Although antigens can display CD22 ligands, the receptor is known to bin...
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Full title
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation
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Record Identifier
TN_cdi_proquest_journals_201424061
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201424061
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0807207106
