Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous S...
Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation
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Publisher
England: Oxford University Press
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Language
English
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England: Oxford University Press
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Abstract
The primary aim of this study was to determine mTOR-pathway activity in primary central nervous system lymphoma (PCNSL), which could be a potential target for therapy. After demonstrating that p-S6 positivity largely exceeded mTOR activity, we aimed to identify other pathways that may lead to S6 phosphorylation. We measured mTOR activit...
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Full title
Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation
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TN_cdi_proquest_journals_2021753290
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2021753290
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ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1093/jnen/nlx121
