PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β^sub 2^...
PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β^sub 2^-Adrenergic Receptors and Adenylyl Cyclase 6
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New York: American Thoracic Society
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English
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New York: American Thoracic Society
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Two cAMP signaling compartments centered on adenylyl cyclase (AC) exist in human airway smooth muscle (HASM) cells, one containing ß2-adrenergic receptor AC6 and another containing E prostanoid receptor AC2. We hypothesized that different PDE isozymes selectively regulate cAMP signaling in each compartment. According to RNA-sequencing data, 18 of 2...
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Full title
PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β^sub 2^-Adrenergic Receptors and Adenylyl Cyclase 6
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TN_cdi_proquest_journals_2031265310
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2031265310
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E-ISSN
1535-4989
DOI
10.1165/rcmb.2017-0294OC
