Intragenic ERBB2 kinase mutations in tumours
Intragenic ERBB2 kinase mutations in tumours
About this item
Full title
Author / Creator
Stephens, Philip , Hunter, Chris , Bignell, Graham , Edkins, Sarah , Davies, Helen , Teague, Jon , Stevens, Claire , O'Meara, Sarah , Smith, Raffaella , Parker, Adrian , Barthorpe, Andy , Blow, Matthew , Brackenbury, Lisa , Butler, Adam , Clarke, Oliver , Cole, Jennifer , Dicks, Ed , Dike, Angus , Drozd, Anja , Edwards, Ken , Forbes, Simon , Foster, Rebecca , Gray, Kristian , Greenman, Chris , Halliday, Kelly , Hills, Katy , Kosmidou, Vivienne , Lugg, Richard , Menzies, Andy , Perry, Janet , Petty, Robert , Raine, Keiran , Ratford, Lewis , Shepherd, Rebecca , Small, Alexandra , Stephens, Yvonne , Tofts, Calli , Varian, Jennifer , West, Sofie , Widaa, Sara , Yates, Andrew , Brasseur, Francis , Cooper, Colin S. , Flanagan, Adrienne M. , Knowles, Margaret , Leung, Suet Y. , Louis, David N. , Looijenga, Leendert H. J. , Malkowicz, Bruce , Pierotti, Marco A. , Teh, Bin , Chenevix-Trench, Georgia , Weber, Barbara L. , Yuen, Siu T. , Harris, Grace , Goldstraw, Peter , Nicholson, Andrew G. , Futreal, P. Andrew , Wooster, Richard and Stratton, Michael R.
Publisher
London: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
The protein-kinase family is the most frequently mutated gene family found in human cancer and faulty kinase enzymes are being investigated as promising targets for the design of antitumour therapies. We have sequenced the gene encoding the transmembrane protein tyrosine kinase ERBB2 (also known as HER2 or Neu) from 120 primary lung tumours and ide...
Alternative Titles
Full title
Intragenic ERBB2 kinase mutations in tumours
Authors, Artists and Contributors
Author / Creator
Hunter, Chris
Bignell, Graham
Edkins, Sarah
Davies, Helen
Teague, Jon
Stevens, Claire
O'Meara, Sarah
Smith, Raffaella
Parker, Adrian
Barthorpe, Andy
Blow, Matthew
Brackenbury, Lisa
Butler, Adam
Clarke, Oliver
Cole, Jennifer
Dicks, Ed
Dike, Angus
Drozd, Anja
Edwards, Ken
Forbes, Simon
Foster, Rebecca
Gray, Kristian
Greenman, Chris
Halliday, Kelly
Hills, Katy
Kosmidou, Vivienne
Lugg, Richard
Menzies, Andy
Perry, Janet
Petty, Robert
Raine, Keiran
Ratford, Lewis
Shepherd, Rebecca
Small, Alexandra
Stephens, Yvonne
Tofts, Calli
Varian, Jennifer
West, Sofie
Widaa, Sara
Yates, Andrew
Brasseur, Francis
Cooper, Colin S.
Flanagan, Adrienne M.
Knowles, Margaret
Leung, Suet Y.
Louis, David N.
Looijenga, Leendert H. J.
Malkowicz, Bruce
Pierotti, Marco A.
Teh, Bin
Chenevix-Trench, Georgia
Weber, Barbara L.
Yuen, Siu T.
Harris, Grace
Goldstraw, Peter
Nicholson, Andrew G.
Futreal, P. Andrew
Wooster, Richard
Stratton, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_204571843
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_204571843
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/431525b
